Last Sunday night in Peyton Manning's return to Indianapolis, the Colts beat the Broncos 39-33. Even though the Colts won the game, they suffered an extreme loss: they lost their star wide receiver, Reggie Wayne to a torn ACL. This means looking forward, guys like Darrius Heyward-Bey and T.Y. Hilton will need to step up and become top targets.
Moving on for the Colts, there is a good chance they end their season 12-4. They have Houston twice, Tennessee twice, Arizona, Kansas City, Jacksonville, and Cincinnati. These are all winnable games except possibly at Kansas City and at Cincinnati. In all of these games, they will be missing someone who is little but has a huge impact.
It will be very interesting to see how the loss of Reggie Wayne impacts the rest of the season. I can't wait to see how it plays out!