Can the Jags pull off a win against the Niners, while playing in London. If you ask me, no. The 49ers offense will overpower the Jag's defense, and though Chad Henne has showed signs of greatness, his stardom will have to wait. Colin Kaepernick has an 85.0 passer rating, which, in case you didn't know, is pretty good. Chad Henne, meanwhile, has a 72.9 passer rating, with only 2 touchdowns and 5 interceptions. He also has 1,222 yards, which is actually pretty good for a guy who has only started 4 games this year. Also, there's just the simple fact that the Jags are 0-7, compared to the 49ers 5-2.
My prediction for this game: