| WEEK 16 |
| Thursday, December 18, 2008 |
 |  | Indianapolis Colts@
Jacksonville Jaguars | 8:15 pm ET |  |
| Saturday, December 20, 2008 |
 |  | Baltimore Ravens@
Dallas Cowboys | 8:15 pm ET | |
| Sunday, December 21, 2008 |
 |  | San Diego Chargers@
Tampa Bay Buccaneers | 1:00 pm ET |  |
 |  | Pittsburgh Steelers@
Tennessee Titans | 1:00 pm ET | |
 |  | San Francisco 49ers@
St. Louis Rams | 1:00 pm ET |  |
 |  | Arizona Cardinals@
New England Patriots | 1:00 pm ET | |
 |  | Cincinnati Bengals@
Cleveland Browns | 1:00 pm ET | |
 |  | Miami Dolphins@
Kansas City Chiefs | 1:00 pm ET | |
 |  | New Orleans Saints@
Detroit Lions | 1:00 pm ET | |
 |  | Buffalo Bills@
Denver Broncos | 4:05 pm ET | |
 |  | New York Jets@
Seattle Seahawks | 4:05 pm ET | |
 |  | Houston Texans@
Oakland Raiders | 4:05 pm ET | |
 |  | Atlanta Falcons@
Minnesota Vikings | 4:15 pm ET | |
 |  | Philadelphia Eagles@
Washington Redskins | 4:15 pm ET | |
 |  | Carolina Panthers@
New York Giants | 8:15 pm ET |  |
| Monday, December 22, 2008 |
 |  | Green Bay Packers@
Chicago Bears | 8:30 pm ET |  |
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