| WEEK 4 |
| Thursday, August 28, 2008 |
 |  | Detroit Lions@
Buffalo Bills | 6:30 pm ET | |
 |  | New York Jets@
Philadelphia Eagles | 6:30 pm ET | |
 |  | Atlanta Falcons@
Baltimore Ravens | 7:00 pm ET | |
 |  | New England Patriots@
New York Giants | 7:00 pm ET | |
 |  | Carolina Panthers@
Pittsburgh Steelers | 7:00 pm ET | |
 |  | St. Louis Rams@
Kansas City Chiefs | 7:00 pm ET | |
 |  | Tennessee Titans@
Green Bay Packers | 7:00 pm ET | |
 |  | Cincinnati Bengals@
Indianapolis Colts | 7:00 pm ET | |
 |  | Jacksonville Jaguars@
Washington Redskins | 7:00 pm ET |  |
 |  | Chicago Bears@
Cleveland Browns | 7:30 pm ET | |
 |  | Tampa Bay Buccaneers@
Houston Texans | 8:00 pm ET | |
 |  | Minnesota Vikings@
Dallas Cowboys | 8:00 pm ET | |
 |  | Miami Dolphins@
New Orleans Saints | 8:00 pm ET | |
| Friday, August 29, 2008 |
 |  | San Diego Chargers@
San Francisco 49ers | 10:00 pm ET | |
 |  | Denver Broncos@
Arizona Cardinals | 10:00 pm ET | |
 |  | Oakland Raiders@
Seattle Seahawks | 10:00 pm ET | |
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