| WEEK 1 |
| Thursday, August 7, 2008 |
 |  | New York Giants@
Detroit Lions | 7:00 pm ET | |
 |  | Baltimore Ravens@
New England Patriots | 7:30 pm ET | |
 |  | New York Jets@
Cleveland Browns | 7:30 pm ET | |
 |  | New Orleans Saints@
Arizona Cardinals | 8:00 pm ET |  |
 |  | Kansas City Chiefs@
Chicago Bears | 8:00 pm ET | |
| Friday, August 8, 2008 |
 |  | Philadelphia Eagles@
Pittsburgh Steelers | 7:30 pm ET | |
 |  | Seattle Seahawks@
Minnesota Vikings | 8:00 pm ET | |
 |  | San Francisco 49ers@
Oakland Raiders | 10:00 pm ET | |
| Saturday, August 9, 2008 |
 |  | Buffalo Bills@
Washington Redskins | 7:00 pm ET | |
 |  | Tampa Bay Buccaneers@
Miami Dolphins | 7:30 pm ET | |
 |  | Atlanta Falcons@
Jacksonville Jaguars | 7:30 pm ET | |
 |  | Indianapolis Colts@
Carolina Panthers | 7:30 pm ET | |
 |  | Denver Broncos@
Houston Texans | 8:00 pm ET | |
 |  | St. Louis Rams@
Tennessee Titans | 8:00 pm ET | |
 |  | Dallas Cowboys@
San Diego Chargers | 10:00 pm ET | |
| Monday, August 11, 2008 |
 |  | Cincinnati Bengals@
Green Bay Packers | 8:00 pm ET | |
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